Retinitis pigmentosa or RP is a hereditary disease which affects the retina and results in progressive and irreversible blindness. With advancements in the delivery of health care services always on the rise in india, stem cell therapy has been identified as a likely means of curing Retinitis Pigmentosa in India. It is hard to decide on stem cell therapy. Thus, it is prudent to understand the differences of treatments that are available, and how to select a treatment appropriately.
Stem cells and their application in the treatment of Retinitis Pigmentosa.
Stem cells are biological entities that are capable of self-renewal and have varied features that can seriously hinder the formation of other biological structures. In such a scenario, Retinitis Pigmentosa is fully understood when Stem Cell Therapy is used.
Stem cell also operates on creating new tissue inside the retina along with repairing present genetic defects of RP. It is a process that is related to various types of stem cells.
Types of Stem Cells Used in the Treatment of Retinal Pigment Epithelium
Embryonic Stem Cells (ESCs) are multipotent, and they can be differentiated into any cell type in the body, including retinal cells. AESC-based therapies attempt to offer a natural substitute for the diseased photoreceptors in the form of functional retinal cells.
Adult stem cells consist of mesenchymal stem cells and retinal progenitor cells. Of these, retinal progenitor cells are from the retina and can regenerate new retinal cells. The other stem cell, mesenchymal stem cells, might be from the bone marrow or adipose tissues and can help in neuroprotection and sustaining retinal health by suppressing the inflammatory process. Induced Pluripotent Stem Cells (iPSCs) are derived from adult somatic cells by reversing these cells to a more embryonic-like state. In addition, this is done to allow the creation of specialized cells derived from a patient’s retina, thereby eradicating the problem of rejection by the body.
Evaluating Treatment Options
Stage of Disease: The stage of retinitis pigmentosa (RP) can, in fact, determine the particular stem cell therapy that the patient receives. However, the early and late stages of RP can have variations in the kind of therapeutic intervention used. In the early stages, cell replacement therapies can be more effective, whereas the later stages can require a combination of stem cell therapy with other therapies to reverse the path of RP and restore function.
Research and Clinical Trials: The therapies to be selected should be supported by evidence or research that is recommended. The research acquired should include treatment modalities that have been demonstrated to work effectively in healthcare centers.
Personalization: The treatment with iPSCs is customized for the patient in order to allow the generation of patient-specific retinal cells. The treatment may be especially useful in determining the most probable genetic mutations in a person.
Conclusion.
The therapy you are planning to undergo should have been thoroughly researched and proven safe for application. Seeking advice from the doctors in StemCellCure, who are experts in stem cell therapy, can help in determining the optimal practice and avoiding the risk of side effects.