Stem cell therapy
All other cells that have specialised functions can be produced from stem cells. Stem cells divide to create daughter cells, which go on to either develop into additional stem cells or specialised cells like blood, brain, or bone cells. As a potential treatment for injured tissue or cells, stem cells are being explored.
- Stem cells replace diseased or compromised cells.
The ability to renew and repair tissue is one of its properties.
- Both transplants and regenerative medicine employ them.
Stem cell’s origin
They are termed blastocysts and are derived from embryos that are three to five days old. These cells are pluripotent stem cells, which may divide to produce several types of body cells.
Adult tissue, such as bone marrow or fat, has a tiny number of adult stem cells. There is a limit to these cells’ capacity to proliferate.
Perinatal stem cells—Stem cells can differentiate into many types of cells and are present in the umbilical cord fluid and amniotic fluid throughout pregnancy.
Treatment with stem cells for spinal cord damage
Mesenchymal stem cells, hematopoietic stem cells, neural stem cells, pluripotent stem cells, and embryonic stem cells are popular forms of Stem Cell Therapy in India used to treat spinal cord injury (SCI), a neurological condition.
There are two types of spinal cord injuries: original injuries and subsequent injuries. Primary injuries are those that result from an external force or a vascular injury, which destroys the spinal cord’s nerves.
In order to treat spinal cord injuries, stem cell therapy for SCI includes stem cell transplantation, which can restore damaged nerve cells and tissue and encourage axonal development and remyelination. Cells travel to the site of the lesion and start the healing process. They also release trophic factors to halt neuronal degeneration and induce angiogenesis. Spasms, sensation, respiratory symptoms, circulatory control, discomfort, and sadness are all signs of a spinal cord injury. Within six months of treatment, inflammation is at a low level, and stem cell therapy promotes neuroprotection and neuroregeneration for the growth of new synapses and axons.
Stem cell therapy for muscular dystrophy
A hereditary condition called muscular dystrophy causes loss of muscle mass and weakening. Adult muscle cells have the ability to regenerate, and this subgroup is known as satellite cells. Muscular dystrophy stem cell therapy transmits the progressive muscle protein and restores the stem pool. These are the main cells involved in the regeneration of skeletal muscle. Muscular dystrophy stem cell therapy plays a part in tissue remodelling, reducing inflammation, and preventing cell death. Treatment strategies for muscular dystrophy include cell fusion and differentiation, cytokine production, increased oxygen delivery, and vascularization of the damaged area.
Role of stem cell therapy in MD
Strengthen the neuromuscular junction;
Muscle healing
Stem cell pool replenishment
Neoangiogenesis
Anti-inflammatory paracrine impact
Anti-fibrotic effect
Anti-apoptotic effect
Treatment with stem cells for cerebral palsy
Cerebral palsy is a non-progressive neurological condition that impairs movement due to a lack of muscular coordination.
Ataxia, spasticity, weakness, toe walking, drooling, tremor, and trouble with motor function are some of the symptoms.
Stem cell therapy for cerebral palsy treatment
Stem cells can restore damaged brain cells and tissues, and they can also promote the growth of new blood vessels, stop cells from dying, and create new neural networks that can be used to learn new skills.
Stem cells can be injected intravenously or extracted via lumbar puncture, after which they grow into nerve cells and link with other cells.
Treatment using stem cells for motor neuron disease
Due to damage to motor neuron cells, which transmit signals through the spinal cord to the muscular nerve cell for movement, motor neuron illness causes weakness in the body. Amyotrophic lateral sclerosis, primary lateral sclerosis, progressive bulbar palsy, progressive muscular atrophy, Kennedy disease, and hirayama disease are all signs of motor neuron disease.
In order to repair tissues, Stem Cells Treatment in India can move and separate into distinct types of brain cells. Increase the number of cells. Motor neurons are renewed by cells like glial cells and stem cells, but MND is caused by an increase in the axonal degeneration of motor neurons in the spinal cord and motor cortex. Because bone marrow contains both hematopoietic cells and mesenchymal progenitor cells, it can effectively infuse the spinal cord region affected by motor neuron illness. Renewing is accomplished by increasing the supply of bone marrow cells.